2020

Asthmatic Bronchial Smooth Muscle Increases CCL5-Dependent Monocyte Migration in Response to Rhinovirus-Infected Epithelium.

Allard B, Levardon H, Esteves P, Celle A, Maurat E, Thumerel M, Girodet PO, Trian T, Berger P.

Front Immunol. 2020 Jan 6;10:2998. doi: 10.3389/fimmu.2019.02998. eCollection 2019.

2019

Determination of reliable lung function parameters in intubated mice.

Bonnardel E, Prevel R, Campagnac M, Dubreuil M, Marthan R, Berger P, Dupin I.

Respir Res. 2019 Sep 14;20(1):211. doi: 10.1186/s12931-019-1177-9

 

Fibrocyte accumulation in the airway walls of COPD patients.

Dupin I, Thumerel M, Maurat E, Coste F, Eyraud E, Begueret H, Trian T, Montaudon M, Marthan R, Girodet PO, Berger P.

Eur Respir J. 2019 Jun 13. pii: 1802173. doi: 10.1183/13993003.02173-2018. [Epub ahead of print]

Chemokines in COPD: From Implication to Therapeutic Use.

Henrot P, Prevel R, Berger P, Dupin I.

Int J Mol Sci. 2019 Jun 6;20(11). pii: E2785. doi: 10.3390/ijms20112785. Review.

 

Automated Volumetric Quantification of Emphysema Severity by Using Ultrashort Echo Time MRI: Validation in Participants with Chronic Obstructive Pulmonary Disease.

Benlala I, Berger P, Girodet PO, Dromer C, Macey J, Laurent F, Dournes G.

Radiology. 2019 Jul;292(1):216-225. doi: 10.1148/radiol.2019190052. Epub 2019 Jun 4

Intestinal Inflammation in Children with Cystic Fibrosis Is Associated with Crohn's-Like Microbiota Disturbances.

Enaud R, Hooks KB, Barre A, Barnetche T, Hubert C, Massot M, Bazin T, Clouzeau H, Bui S, Fayon M, Berger P, Lehours P, Bébéar C, Nikolski M, Lamireau T, Delhaes L, Schaeverbeke T.

J Clin Med. 2019 May 10;8(5). pii: E645. doi: 10.3390/jcm8050645

 

Quantitative CT assessment of bronchial and vascular alterations in severe precapillary pulmonary hypertension.

Coste F, Benlala I, Dournes G, Dromer C, Blanchard E, Girodet PO, Montaudon M, Baldacci F, Picard F, Marthan R, Laurent F, Berger P.

Int J Chron Obstruct Pulmon Dis. 2019 Feb 11;14:381-389. doi: 10.2147/COPD.S177638. eCollection 2019.

 

CT evaluation of hyperattenuating mucus to diagnose allergic bronchopulmonary aspergillosis in the special condition of cystic fibrosis.

Refait J, Macey J, Bui S, Fayon M, Berger P, Delhaes L, Laurent F, Dournes G.

J Cyst Fibros. 2019 Feb 12. pii: S1569-1993(18)30902-0. doi: 10.1016/j.jcf.2019.02.002. Epub 2019 Feb 12

2018

3D ultrashort echo time MRI of the lung using stack-of-spirals and spherical k-Space coverages: Evaluation in healthy

volunteers and parenchymal diseases.

Dournes G, Yazbek J, Benhassen W, Benlala I, Blanchard E, Truchetet ME, Macey J, Berger P, Laurent F. 

J Magn Reson Imaging. 2018 Dec;48(6):1489-1497. doi: 10.1002/jmri.26212. Epub 2018 Sep 11.

 

The Mycobiome: A Neglected Component in the Microbiota-Gut-Brain Axis.

Enaud R, Vandenborght LE, Coron N, Bazin T, Prevel R, Schaeverbeke T, Berger P, Fayon M, Lamireau T, Delhaes L.

Microorganisms. 2018 Mar 9;6(1). pii: E22. doi: 10.3390/microorganisms6010022. Review.

 

Montelukast reverses airway remodeling in actively sensitized young mice.

Debelleix S, Siao-Him Fa V, Begueret H, Berger P, Kamaev A, Ousova O, Marthan R, Fayon M. 

Pediatr Pulmonol. 2018 Jun;53(6):701-709. doi: 10.1002/ppul.23980. Epub 2018 Mar 1.

 

Fibrocytes in Asthma and Chronic Obstructive Pulmonary Disease: Variations on the Same Theme.

Dupin I, Contin-Bordes C, Berger P. 

Am J Respir Cell Mol Biol. 2018 Mar;58(3):288-298. doi: 10.1165/rcmb.2017-0301PS. Review.

2017

Allergic Bronchopulmonary Aspergillosis in Cystic Fibrosis: MR Imaging of Airway Mucus Contrasts as a Tool for Diagnosis.

Dournes G, Berger P, Refait J, Macey J, Bui S, Delhaes L, Montaudon M, Corneloup O, Chateil JF, Marthan R, Fayon M, Laurent F.

Radiology. 2017 Oct;285(1):261-269. doi: 10.1148/radiol.2017162350. Epub 2017 May 22.

Nasal airway epithelial cell IL-6 and FKBP51 gene expression and steroid sensitivity in asthmatic children.

Fayon M, Lacoste-Rodrigues A, Barat P, Helbling JC, Nacka F, Berger P, Moisan MP, Corcuff JB.

PLoS One. 2017 May 11;12(5):e0177051. doi: 10.1371/journal.pone.0177051. eCollection 2017.

Identification of airway mucosal type 2 inflammation by using clinical biomarkers in asthmatic patients.

Silkoff PE, Laviolette M, Singh D, FitzGerald JM, Kelsen S, Backer V, Porsbjerg CM, Girodet PO, Berger P, Kline JN, Chupp G, Susulic VS, Barnathan ES, Baribaud F, Loza MJ; Airways Disease Endotyping for Personalized Therapeutics (ADEPT) study investigators.

J Allergy Clin Immunol. 2017 Sep;140(3):710-719. doi: 10.1016/j.jaci.2016.11.038. Epub 2017 Jan 13.

2016

CT evaluation of small pulmonary vessels area in patients with COPD with severe pulmonary hypertension.

Coste F, Dournes G, Dromer C, Blanchard E, Freund-Michel V, Girodet PO, Montaudon M, Baldacci F, Picard F, Marthan R, Berger P, Laurent F.

Thorax. 2016 Sep;71(9):830-7. doi: 10.1136/thoraxjnl-2015-207696. Epub 2016 Apr 15.

Lung morphology assessment of cystic fibrosis using MRI with ultra-short echo time at submillimeter spatial resolution.

Dournes G, Menut F, Macey J, Fayon M, Chateil JF, Salel M, Corneloup O, Montaudon M, Berger P, Laurent F.

Eur Radiol. 2016 Nov;26(11):3811-3820. Epub 2016 Feb 2.

Selective dysfunction of p53 for mitochondrial biogenesis induces cellular proliferation in bronchial smooth muscle from asthmatic patients.

Trian T, Allard B, Ozier A, Maurat E, Dupin I, Thumerel M, Ousova O, Gillibert-Duplantier J, Le Morvan V, Begueret H, Girodet PO, Marthan R, Berger P.

J Allergy Clin Immunol. 2016 Jun;137(6):1717-1726.e13. doi: 10.1016/j.jaci.2015.10.031. Epub 2015 Dec 11.

Blood fibrocytes are recruited during acute exacerbations of chronic obstructive pulmonary disease through a CXCR4-dependent pathway.

Dupin I, Allard B, Ozier A, Maurat E, Ousova O, Delbrel E, Trian T, Bui HN, Dromer C, Guisset O, Blanchard E, Hilbert G, Vargas F, Thumerel M, Marthan R, Girodet PO, Berger P.

J Allergy Clin Immunol. 2016 Apr;137(4):1036-1042.e7. doi: 10.1016/j.jaci.2015.08.043. Epub 2015 Oct 23.

Bronchial Smooth Muscle Remodeling in Nonsevere Asthma.

Girodet PO, Allard B, Thumerel M, Begueret H, Dupin I, Ousova O, Lassalle R, Maurat E, Ozier A, Trian T, Marthan R, Berger P.

Am J Respir Crit Care Med. 2016 Mar 15;193(6):627-33. doi: 10.1164/rccm.201507-1404OC.

2015

Prevalence and risk factors for COPD in farmers: a cross-sectional controlled study.

Guillien A, Puyraveau M, Soumagne T, Guillot S, Rannou F, Marquette D, Berger P, Jouneau S, Monnet E, Mauny F, Laplante JJ, Dalphin JC, Degano B.

Eur Respir J. 2016 Jan;47(1):95-103. doi: 10.1183/13993003.00153-2015. Epub 2015 Oct 9.

Microfibrillar-associated protein 4 modulates airway smooth muscle cell phenotype in experimental asthma.

Pilecki B, Schlosser A, Wulf-Johansson H, Trian T, Moeller JB, Marcussen N, Aguilar-Pimentel JA, de Angelis MH, Vestbo J, Berger P, Holmskov U, Sorensen GL.

Thorax. 2015 Sep;70(9):862-72. doi: 10.1136/thoraxjnl-2014-206609. Epub 2015 Jun 2.

An age-wise comparison of human airway smooth muscle proliferative capacity.

Fayon M, Andrieux A, Bara I, Rebola M, Labbé A, Marthan R, Berger P.

PLoS One. 2015 Mar 23;10(3):e0122446. doi: 10.1371/journal.pone.0122446. eCollection 2015.

Calcium channel blocker reduces airway remodeling in severe asthma. A proof-of-concept study.

Girodet PO, Dournes G, Thumerel M, Begueret H, Dos Santos P, Ozier A, Dupin I, Trian T, Montaudon M, Laurent F, Marthan R, Berger P.

Am J Respir Crit Care Med. 2015 Apr 15;191(8):876-83. doi: 10.1164/rccm.201410-1874OC.

House dust mites induce proliferation of severe asthmatic smooth muscle cells via an epithelium-dependent pathway.

Trian T, Allard B, Dupin I, Carvalho G, Ousova O, Maurat E, Bataille J, Thumerel M, Begueret H, Girodet PO, Marthan R, Berger P.

Am J Respir Crit Care Med. 2015 Mar 1;191(5):538-46. doi: 10.1164/rccm.201409-1582OC.

Computed tomographic measurement of airway remodeling and emphysema in advanced chronic obstructive pulmonary disease. Correlation with pulmonary hypertension.

Dournes G, Laurent F, Coste F, Dromer C, Blanchard E, Picard F, Baldacci F, Montaudon M, Girodet PO, Marthan R, Berger P.

Am J Respir Crit Care Med. 2015 Jan 1;191(1):63-70. doi: 10.1164/rccm.201408-1423OC.

Before

Protease activated receptor-2 expression and function in asthmatic bronchial smooth muscle.

Allard B, Bara I, Gilbert G, Carvalho G, Trian T, Ozier A, Gillibert-Duplantier J, Ousova O, Maurat E, Thumerel M, Quignard JF, Girodet PO, Marthan R, Berger P.

PLoS One. 2014 Feb 13;9(2):e86945. doi: 10.1371/journal.pone.0086945. eCollection 2014

Breathing variability and brainstem serotonergic loss in a genetic model of multiple system atrophy.

Flabeau O, Meissner WG, Ozier A, Berger P, Tison F, Fernagut PO.

Mov Disord. 2014 Mar;29(3):388-95. doi: 10.1002/mds.25804. Epub 2014 Jan 17.

A proof-of-concept, randomized, controlled trial of omalizumab in patients with severe, difficult-to-control, nonatopic asthma.

Garcia G, Magnan A, Chiron R, Contin-Bordes C, Berger P, Taillé C, Devouassoux G, de Blay F, Couderc LJ, Didier A, O'Callaghan DS, Girodet PO, Bourdeix I, Le Gros V, Humbert M.

Chest. 2013 Aug;144(2):411-419. doi: 10.1378/chest.12-1961

Ca(2+)-activated K(+) channel-3.1 blocker TRAM-34 attenuates airway remodeling and eosinophilia in a murine asthma model.

Girodet PO, Ozier A, Carvalho G, Ilina O, Ousova O, Gadeau AP, Begueret H, Wulff H, Marthan R, Bradding P, Berger P.

Am J Respir Cell Mol Biol. 2013 Feb;48(2):212-9. doi: 10.1165/rcmb.2012-0103OC. Epub 2012 Nov 29

CT attenuation of the bronchial wall in patients with asthma: comparison with geometric parameters and correlation with function and histologic characteristics.

Lederlin M, Laurent F, Portron Y, Ozier A, Cochet H, Berger P, Montaudon M.

AJR Am J Roentgenol. 2012 Dec;199(6):1226-33. doi: 10.2214/AJR.11.8396.

In vivo micro-CT assessment of airway remodeling in a flexible OVA-sensitized murine model of asthma.

Lederlin M, Ozier A, Dournes G, Ousova O, Girodet PO, Begueret H, Marthan R, Montaudon M, Laurent F, Berger P.

PLoS One. 2012;7(10):e48493. doi: 10.1371/journal.pone.0048493. Epub 2012 Oct 30.

Airway smooth muscle in asthma: just a target for bronchodilation?

Black JL, Panettieri RA Jr, Banerjee A, Berger P.

Clin Chest Med. 2012 Sep;33(3):543-58. doi: 10.1016/j.ccm.2012.05.002. Epub 2012 Jul 11. Review

[Prevention of COPD exacerbation: a fundamental challenge].

Roche N, Aguilaniu B, Burgel PR, Durand-Zaleski I, Dusser D, Escamilla R, Perez T, Raherison C, Similowski T; groupe d’expert « Exacerbations de BPCO ».

Rev Mal Respir. 2012 Jun;29(6):756-74. doi: 10.1016/j.rmr.2012.04.006. Epub 2012 Jun 6. Review. French.

Mean bronchial wall attenuation value in chronic obstructive pulmonary disease: comparison with standard bronchial parameters and correlation with function.

Lederlin M, Laurent F, Dromer C, Cochet H, Berger P, Montaudon M.

AJR Am J Roentgenol. 2012 Apr;198(4):800-8. doi: 10.2214/AJR.11.6895.

Adaptative capacity of mitochondrial biogenesis and of mitochondrial dynamics in response to pathogenic respiratory chain dysfunction.

Benard G, Trian T, Bellance N, Berger P, Lavie J, Espil-Taris C, Rocher C, Eimer-Bouillot S, Goizet C, Nouette-Gaulain K, Letellier T, Lacombe D, Rossignol R.

Antioxid Redox Signal. 2013 Aug 1;19(4):350-65. doi: 10.1089/ars.2011.4244. Epub 2012 Apr 19.

In Vivo Computed Tomography as a Research Tool to Investigate Asthma and COPD: Where Do We Stand?

Dournes G, Montaudon M, Berger P, Laurent F.

J Allergy (Cairo). 2012;2012:972479. doi: 10.1155/2012/972479. Epub 2012 Jan 11.

Role of YKL-40 in bronchial smooth muscle remodeling in asthma.

Bara I, Ozier A, Girodet PO, Carvalho G, Cattiaux J, Begueret H, Thumerel M, Ousova O, Kolbeck R, Coyle AJ, Woods J, Tunon de Lara JM, Marthan R, Berger P.

Am J Respir Crit Care Med. 2012 Apr 1;185(7):715-22. doi: 10.1164/rccm.201105-0915OC. Epub 2012 Jan 26.

The pivotal role of airway smooth muscle in asthma pathophysiology.

Ozier A, Allard B, Bara I, Girodet PO, Trian T, Marthan R, Berger P.

J Allergy (Cairo). 2011;2011:742710. doi: 10.1155/2011/742710. Epub 2011 Dec 11.

β2-Agonist induced cAMP is decreased in asthmatic airway smooth muscle due to increased PDE4D.

Trian T, Burgess JK, Niimi K, Moir LM, Ge Q, Berger P, Liggett SB, Black JL, Oliver BG.

PLoS One. 2011;6(5):e20000. doi: 10.1371/journal.pone.0020000. Epub 2011 May 17.

[Pathophysiology of asthma].

Ozier A, Bara I, Girodet PO, Marthan R, Berger P.

Rev Prat. 2011 Mar;61(3):339-45. French.

Airway remodeling in asthma: new mechanisms and potential for pharmacological intervention.

Girodet PO, Ozier A, Bara I, Tunon de Lara JM, Marthan R, Berger P.

Pharmacol Ther. 2011 Jun;130(3):325-37. doi: 10.1016/j.pharmthera.2011.02.001. Epub 2011 Feb 17. Review.

Control maintenance can be predicted by exhaled NO monitoring in asthmatic patients.

Ozier A, Girodet PO, Bara I, Tunon de Lara JM, Marthan R, Berger P.

Respir Med. 2011 Jul;105(7):989-96. doi: 10.1016/j.rmed.2011.01.006. Epub 2011 Feb 3.

Bronchial measurements in patients with asthma: comparison of quantitative thin-section CT findings with those in healthy subjects and correlation with pathologic findings.

Montaudon M, Lederlin M, Reich S, Begueret H, Tunon-de-Lara JM, Marthan R, Berger P, Laurent F.

Radiology. 2009 Dec;253(3):844-53. doi: 10.1148/radiol.2533090303. Epub 2009 Sep 29.

Airway remodeling in a mouse asthma model assessed by in-vivo respiratory-gated micro-computed tomography.

Lederlin M, Ozier A, Montaudon M, Begueret H, Ousova O, Marthan R, Berger P, Laurent F.

Eur Radiol. 2010 Jan;20(1):128-37. doi: 10.1007/s00330-009-1541-0. Epub 2009 Aug 14.

Bronchial morphometry in smokers: comparison with healthy subjects by using 3D CT.

Montaudon M, Berger P, Lederlin M, Marthan R, Tunon-de-Lara JM, Laurent F.

Eur Radiol. 2009 Jun;19(6):1328-34. doi: 10.1007/s00330-008-1284-3. Epub 2009 Jan 24.

Human airway smooth muscle promotes human lung mast cell survival, proliferation, and constitutive activation: cooperative roles for CADM1, stem cell factor, and IL-6.

Hollins F, Kaur D, Yang W, Cruse G, Saunders R, Sutcliffe A, Berger P, Ito A, Brightling CE, Bradding P.

J Immunol. 2008 Aug 15;181(4):2772-80

Bronchial smooth muscle remodeling involves calcium-dependent enhanced mitochondrial biogenesis in asthma.

Trian T, Benard G, Begueret H, Rossignol R, Girodet PO, Ghosh D, Ousova O, Vernejoux JM, Marthan R, Tunon-de-Lara JM, Berger P.

J Exp Med. 2007 Dec 24;204(13):3173-81. Epub 2007 Dec 3.

Bronchial measurement with three-dimensional quantitative thin-section CT in patients with cystic fibrosis.

Montaudon M, Berger P, Cangini-Sacher A, de Dietrich G, Tunon-de-Lara JM, Marthan R, Laurent F.

Radiology. 2007 Feb;242(2):573-81. Epub 2006 Dec 19.

Assessment of airways with three-dimensional quantitative thin-section CT: in vitro and in vivo validation.

Montaudon M, Berger P, de Dietrich G, Braquelaire A, Marthan R, Tunon-de-Lara JM, Laurent F.

Radiology. 2007 Feb;242(2):563-72. Epub 2006 Dec 19.

Airway smooth muscle and mast cell-derived CC chemokine ligand 19 mediate airway smooth muscle migration in asthma.

Kaur D, Saunders R, Berger P, Siddiqui S, Woodman L, Wardlaw A, Bradding P, Brightling CE.

Am J Respir Crit Care Med. 2006 Dec 1;174(11):1179-88. Epub 2006 Sep 7.

Increased secretion of leukemia inhibitory factor by immature airway smooth muscle cells enhances intracellular signaling and airway contractility.

Fayon M, Rebola M, Berger P, Daburon S, Ousova O, Lavrand F, Moukaïla B, Pujol W, Taupin JL, Labbé A, Molimard M, Marthan R.

Am J Physiol Lung Cell Mol Physiol. 2006 Aug;291(2):L244-51. Epub 2006 Feb 17.

Fraktalkine produced by airway smooth muscle cells contributes to mast cell recruitment in asthma.

El-Shazly A, Berger P, Girodet PO, Ousova O, Fayon M, Vernejoux JM, Marthan R, Tunon-de-Lara JM.

J Immunol. 2006 Feb 1;176(3):1860-8.

RNA interference decreases PAR-2 expression and function in human airway smooth muscle cells.

Trian T, Girodet PO, Ousova O, Marthan R, Tunon-de-Lara JM, Berger P.

Am J Respir Cell Mol Biol. 2006 Jan;34(1):49-55. Epub 2005 Sep 29.

Airway wall thickness in cigarette smokers: quantitative thin-section CT assessment.

Berger P, Perot V, Desbarats P, Tunon-de-Lara JM, Marthan R, Laurent F.

Radiology. 2005 Jun;235(3):1055-64. Epub 2005 Apr 15.

Bronchial Remodeling

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